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Mircette
Mircette Properties
About Mircette
Mircette is a prescription-only combined oral contraceptive that contains .15 mg desogestrel and .02 mg ethinyl estradiol per tablet. It belongs to the class of combined hormonal contraceptives and is used to prevent pregnancy and to manage hormone-related conditions such as dysmenorrhea and acne. In Singapore the medication is regulated by the Health Sciences Authority and is dispensed only with a valid prescription from a qualified healthcare professional.
What is Mircette?
Mircette is a brand-name oral tablet that combines a progestogenic component (desogestrel) with an estrogenic component (ethinyl estradiol). The product is classified as a combined oral contraceptive (COC) and is approved for use as a reversible method of contraception as well as for certain hormone-therapy indications, including the treatment of moderate acne and the regulation of menstrual cycles. The formulation is marketed in a 28-day cycle pack, with 21 active tablets followed by a hormone-free interval.
How Mircette Works
Desogestrel is a third-generation progestin that exerts its contraceptive effect primarily by suppressing the mid-cycle surge of luteinising hormone (LH) and follicle-stimulating hormone (FSH). This inhibition prevents ovulation, the release of a mature oocyte. Ethinyl estradiol, a synthetic estrogen, stabilises the endometrium and provides negative feedback to the hypothalamic-pituitary axis, reinforcing the suppression of LH and FSH. Together, the two hormones also thicken cervical mucus, making it hostile to sperm penetration, and induce changes in the endometrial lining that reduce the likelihood of implantation should fertilisation occur. Oral absorption is rapid; desogestrel is converted to its active metabolite, etonogestrel, while ethinyl estradiol undergoes hepatic metabolism via cytochrome P450 enzymes. The typical onset of contraceptive efficacy is within 7 days of consistent daily dosing, and steady-state hormone levels are achieved after about two weeks of use.
Why Mircette is Used for Contraceptives, Hormone Therapy
- Effective Ovulation Suppression - The low-dose desogestrel component reliably prevents the LH surge, achieving a Pearl Index of <1 pregnancy per 100 woman-years when taken correctly.
- Improved Cycle Control - Ethinyl estradiol provides stable estrogen exposure, reducing breakthrough bleeding and resulting in predictable withdrawal bleeding during the hormone-free interval.
- Acne Management - Clinical trials have shown that combined regimens containing desogestrel and ethinyl estradiol improve moderate acne by decreasing androgenic stimulation of sebaceous glands.
- Dysmenorrhea Relief - The estrogen component stabilises endometrial growth, lessening prostaglandin-mediated uterine contractions that cause painful periods.
- First-Line Recommendation - Singapore’s Ministry of Health guidelines list low-dose combined oral contraceptives as a preferred initial therapy for women without contraindications, due to their high efficacy, oral convenience, and non-invasive nature.
- Cost-Effectiveness - Compared with newer hormonal agents, the well-established safety profile and generic availability of the active ingredients make Mircette a financially sensible option for many patients.
Is Mircette Right for You?
Mircette is suitable for healthy women of reproductive age who desire reliable contraception and have no contraindications such as a history of thromboembolic disease, uncontrolled hypertension, or severe migraine with aura. It can also be considered for patients seeking treatment of moderate acne or menstrual irregularities, provided they do not require higher-dose estrogen therapy. Special populations require additional caution:
- Women over 35 who smoke should avoid combined oral contraceptives due to an increased risk of cardiovascular events.
- Pregnancy or breastfeeding are absolute contraindications; alternative methods must be used.
- Renal or hepatic impairment may necessitate dose adjustment or alternative contraception.
- Patients on interacting medications (e.g., certain anticonvulsants, rifampin) may experience reduced hormone levels and should discuss alternative options with their prescriber.
Taking Mircette Effectively
Consistent daily intake at the same time each day maximises plasma hormone stability. Each tablet should be swallowed whole with water; food does not significantly affect absorption, but taking the pill with a meal can reduce gastrointestinal discomfort. If a dose is missed by more than 12 hours, the missed tablet should be taken as soon as remembered, and the subsequent tablets taken at the usual time, resulting in a short period of double dosing. No additional contraception is required if a single tablet is missed, but if two or more consecutive tablets are missed, a backup method (e.g., barrier protection) should be used for the next seven days. For travel across time zones, the dosing schedule can be adjusted by up to two hours without compromising efficacy, provided the interval between tablets remains consistent.
Understanding Side Effects and How to Manage Them
Common side effects-such as mild nausea, breast tenderness, and occasional spotting-are generally hormone-related and often resolve within the first three cycles as the body adapts. Taking the pill with food, staying hydrated, and avoiding excessive caffeine can lessen nausea. Breast tenderness may be alleviated by a supportive bra and limiting high-fat meals that can increase estrogen levels. Spotting is typically transient; using a non-hormonal backup method for the first month can provide reassurance.
Serious adverse events are rare but require prompt medical attention:
- Venous thromboembolism (VTE) - sudden leg swelling, pain, or shortness of breath.
- Hypertensive crisis - severe headache, visual changes, or chest pain.
- Hepatic dysfunction - jaundice, dark urine, or right-upper-quadrant pain.
Patients experiencing any of these symptoms should discontinue Mircette and seek immediate care.
Buying Mircette from Our Online Pharmacy
Accessing Mircette through a reputable online channel can simplify the prescription-fulfilment process, especially for individuals living in areas with limited pharmacy stock or for those who value discreet delivery.
Why Choose Our Service?
Our platform connects you with licensed pharmacies that comply with Singapore’s Health Sciences Authority regulations, ensuring that every tablet meets stringent quality standards.
Quality & Safety
We partner with internationally accredited suppliers that adhere to Good Manufacturing Practice (GMP) guidelines and undergo routine third-party testing for potency and purity.
Pricing & Access
Mircette is offered at a competitive price point, with a 10 % discount applied automatically to all repeat orders. Bulk purchasing options are available for patients who require long-term therapy.
Discreet Delivery
Orders are shipped in unmarked packaging, typically arriving within 5-7 business days for express delivery or 2-3 weeks for standard service, with full tracking throughout the journey.
Frequently Asked Questions
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Can Mircette be started immediately after a missed period? Yes, as long as the missed tablets are taken promptly and a backup method is used for the first seven days, Mircette can be initiated without waiting for the next menstrual cycle.
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Does Mircette protect against sexually transmitted infections (STIs)? No, combined oral contraceptives provide no barrier against STIs; using condoms in addition to Mircette is recommended for protection.
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What should I do if I experience persistent headaches? Persistent or severe headaches, especially with visual disturbances, may signal a migraine with aura, which is a contraindication for continued use. Contact your healthcare provider to discuss alternative contraception.
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Is it safe to take Mircette while on antibiotics? Most antibiotics do not affect hormonal efficacy. However, rifampin and some antiepileptic drugs can lower hormone levels; discuss your medication list with a prescriber.
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Can Mircette be used to treat severe acne? While it may improve moderate acne, severe cases often require higher-dose estrogen or adjunctive therapies. Consultation with a dermatologist is advised.
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How does weight affect Mircette’s effectiveness? Body weight does not significantly alter the pharmacodynamics of low-dose combined pills, but extreme obesity may slightly reduce efficacy; individualized counseling is recommended.
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Is there a risk of bone loss with long-term use? Combined oral contraceptives have a neutral or slightly protective effect on bone mineral density in most women; however, calcium-rich diets and weight-bearing exercise are beneficial.
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Can I switch from Mircette to a progestin-only pill? Yes, but a 7-day overlap with a non-hormonal method is advised during the transition to maintain contraceptive coverage.
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What is the recommended age range for Mircette? The product is generally indicated for women aged 15-45 years who meet the health criteria for combined hormonal contraception.
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How should I store Mircette? Keep tablets in original packaging, away from heat, moisture, and direct sunlight; do not refrigerate.
Glossary
- Desogestrel
- A third-generation synthetic progestin that is metabolised to etonogestrel, which suppresses ovulation by inhibiting LH and FSH secretion.
- Ethinyl Estradiol
- A synthetic estrogen used in combined oral contraceptives to stabilise the endometrium and provide negative feedback to the hypothalamic-pituitary axis.
- Pearl Index
- A statistical measure of contraceptive effectiveness representing the number of pregnancies per 100 woman-years of exposure.
Disclaimer
The information provided about Mircette is for general knowledge only. It does not replace professional medical consultation. All treatment decisions, including those regarding off-label use, should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Mircette for individuals who may have limited availability through traditional pharmacies, prescription-based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.
