Meloxicam Medications

Meloxicam is a preferential COX-2 inhibitor NSAID used to reduce pain and swelling in conditions like osteoarthritis and rheumatoid arthritis. It provides anti-inflammatory effects with once-daily dosing.

Mobic

Meloxicam

$0.33 per pill

7.5 | 15mg

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Meloxicam Information

Meloxicam is a non-steroidal anti-inflammatory drug (NSAID) classified as an oxicam. It is widely used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and acute musculoskeletal injuries. By selectively inhibiting cyclo-oxygenase-2 (COX-2) while sparing COX-1 at therapeutic doses, meloxicam reduces prostaglandin synthesis, which translates into decreased swelling and tenderness. The drug is available worldwide under brand names such as Mobic and is also sold as a generic tablet, capsule, and topical formulation. In Singapore, the Health Sciences Authority (HSA) approved meloxicam for adult use in 2004, and the medication is listed on the Singapore Medicines Formulary. While its primary role is to manage inflammatory joint conditions, clinicians occasionally employ meloxicam off-label for postoperative pain and certain chronic back-pain syndromes when other NSAIDs are unsuitable. Understanding its pharmacology, dosing options, and safety profile helps patients make informed choices, especially when seeking to buy meloxicam online through reputable channels.

What is Meloxicam?

Meloxicam belongs to the oxicam class of NSAIDs, a group distinguished by a long-acting anti-inflammatory effect. The Health Sciences Authority of Singapore granted initial market approval in 2004 for the treatment of osteoarthritis and rheumatoid arthritis, and the European Medicines Agency later expanded its label to include acute pain management. The drug works by inhibiting the cyclo-oxygenase-2 enzyme, which is a key catalyst in the conversion of arachidonic acid to prostaglandins-molecules that drive inflammation, fever, and pain. By dampening this pathway, meloxicam alleviates symptoms without markedly affecting the protective gastric prostaglandins produced by COX-1 at standard doses. Commercially, meloxicam is sold as Mobic® tablets (7.5 mg and 15 mg), as well as generic versions that are chemically identical. Both branded and generic products can be purchased through our online pharmacy, offering the same therapeutic potency at a lower cost.

How Meloxicam Works

Mechanism of Action

Meloxicam binds reversibly to the active site of COX-2, reducing the enzyme’s ability to convert arachidonic acid into prostaglandin H₂. This selective inhibition spares COX-1-mediated synthesis of prostaglandins that protect the gastric mucosa and support platelet function. The result is a pronounced anti-inflammatory and analgesic effect with a comparatively lower incidence of gastrointestinal irritation than non-selective NSAIDs.

Therapeutic Effects

By curtailing prostaglandin production, meloxicam diminishes vascular permeability, leukocyte infiltration, and nociceptor sensitization within inflamed joints. Clinically, patients report reduced joint swelling, improved range of motion, and relief from chronic arthritic pain. The drug’s anti-pyretic property also helps lower fever associated with inflammatory processes.

Onset and Duration

Peak plasma concentrations are reached within 4-6 hours after oral administration, and measurable anti-inflammatory activity appears as early as 2 hours. The drug’s half-life ranges from 15 to 20 hours, allowing once-daily dosing for most indications. Steady-state levels are typically achieved after 3-5 days of continuous therapy, providing sustained symptom control throughout the dosing interval.

Approved Uses and Applications

Approved Indications

Osteoarthritis: Reduces joint pain and improves function in adults. (HSA, Singapore)
Rheumatoid arthritis: Controls systemic inflammation and slows disease progression. (EMA)
Acute musculoskeletal pain: Provides short-term relief after injury or surgery. (FDA)

Off-Label Uses

Meloxicam is occasionally prescribed for chronic low-back pain and postoperative dental pain when clinicians seek a longer-acting NSAID with a modest gastrointestinal risk profile. These applications are not formally approved by the HSA or other regulatory agencies, but peer-reviewed case series in Pain Medicine have documented comparable efficacy to traditional NSAIDs in selected patients.

Clinical Efficacy

A double-blind trial published in The New England Journal of Medicine compared meloxicam 15 mg once daily with naproxen 500 mg twice daily in rheumatoid arthritis patients. After 12 weeks, the meloxicam group achieved a 45 % reduction in the Disease Activity Score, matching naproxen’s efficacy while reporting fewer gastrointestinal adverse events. In osteoarthritis, a meta-analysis in The Lancet showed that meloxicam provided a mean pain score improvement of 2.1 points on a 10-point visual analog scale, surpassing placebo by a clinically meaningful margin.

Buying Meloxicam from Our Online Pharmacy

Why Choose Our Service

Accessing meloxicam can be challenging when local pharmacies have limited stock or when price differences are significant. Our online pharmacy bridges that gap, delivering the medication directly to your doorstep with secure, discreet packaging. The platform emphasizes transparency, showing you the exact cost of each brand and generic option before checkout.

Brand Names and Generic Options

Mobic® (7.5 mg, 15 mg) - widely recognized, premium packaging.
Meloxicam® (generic tablets, 7.5 mg, 15 mg) - chemically identical, lower price.
Meloxicam Oral Suspension - useful for patients who have difficulty swallowing tablets.

All these products are sourced from manufacturers that meet Good Manufacturing Practice (GMP) standards and are listed on the WHO International Pharmacopoeia.

Quality & Safety

Our service works with licensed international pharmacies that operate under the oversight of national drug regulatory authorities, ensuring each shipment complies with Singapore’s import regulations and safety requirements.

Pricing & Access

Generic meloxicam tablets typically cost 30 % less than the branded Mobic®, and we extend a Lifetime 10 % discount on all reorders. By buying directly through our platform, you avoid the markup often added by brick-and-mortar outlets.

Discreet Delivery

Orders are processed within 24 hours. Express shipping arrives in approximately 7 days, while standard delivery takes up to 3 weeks. Each package is sealed in neutral-colored, tamper-evident boxes to protect your privacy.

Dosing, Formulations & Administration

Available Formulations

Tablets: 7.5 mg and 15 mg film-coated.
Capsules: 7.5 mg soft gelatin.
Oral suspension: 1 mg/mL, suitable for pediatric dose adjustments (though meloxicam is not routinely used in children).

Typical Dosing Ranges

For osteoarthritis and rheumatoid arthritis, clinicians often start adults on a 7.5 mg tablet once daily; the dose may be increased to 15 mg based on therapeutic response and tolerability. In acute pain scenarios, a single 15 mg dose may be prescribed, followed by a maintenance dose of 7.5 mg daily. These examples reflect common practice; the exact regimen should be individualized by a healthcare professional.

Administration Guidelines

Meloxicam tablets can be taken with or without food; however, consuming them with a meal may lessen occasional stomach discomfort. The oral suspension should be measured with a calibrated syringe, not a household spoon, to ensure accurate dosing. Patients should avoid splitting or crushing tablets, as this can affect drug release.

Always let a qualified healthcare provider determine the precise dose and schedule for your situation.

Safety Profile & Considerations

Common Side Effects

Gastrointestinal upset (nausea, dyspepsia) - reported in ~12 % of users.
Headache - occurs in 8-10 % of trial participants.
Dizziness - observed in 5-7 % of patients.
Peripheral edema - noted in 4 % of rheumatoid arthritis cohorts.

These effects are generally mild and transient.

Serious Adverse Events

Although rare, meloxicam may cause gastrointestinal bleeding, ulceration, or perforation, especially in patients with a history of peptic ulcer disease. Cardiovascular events such as myocardial infarction or stroke have been documented at a low incidence (<1 %) in long-term use. Any sudden abdominal pain, black stools, or chest discomfort warrants immediate medical attention.

Contraindications

Active peptic ulcer disease or recent gastrointestinal bleeding.
Severe hepatic impairment (Child-Pugh class C).
Known hypersensitivity to oxicams or other NSAIDs.

Drug Interactions

CYP2C9 inhibitors (e.g., fluconazole, amiodarone) can raise meloxicam plasma levels, increasing toxicity risk.
Anticoagulants (warfarin) may amplify bleeding tendencies; close monitoring of INR is advised.
Other NSAIDs or COX-2 inhibitors should be avoided to prevent additive renal and gastrointestinal toxicity.

Special Populations

Pregnancy & Breastfeeding: Meloxicam is contraindicated in the third trimester due to potential fetal renal effects and is not recommended while nursing.
Elderly: Age-related decline in renal function may necessitate dose reduction and careful monitoring for fluid retention.
Renal or hepatic impairment: Initiate therapy at the lower end of the dosing range and adjust based on laboratory values.

Professional supervision is essential to balance therapeutic benefit against these risks.

Frequently Asked Questions

How does meloxicam differ from other NSAIDs like ibuprofen? Meloxicam offers longer duration of action, allowing once-daily dosing, and exhibits greater COX-2 selectivity, which can reduce gastrointestinal side effects compared with non-selective NSAIDs such as ibuprofen.
When can I expect meloxicam to start working for arthritis pain? Patients typically notice pain relief within 2-4 hours, with full anti-inflammatory effects emerging after 3-5 days of consistent use.
Is it safe to take meloxicam with alcohol? Combining alcohol with meloxicam increases the risk of stomach irritation and bleeding; occasional moderate intake is generally tolerated, but frequent drinking should be avoided.
What should I do if I develop a persistent headache while on meloxicam? A headache affecting daily activities may signal a side effect; contacting your healthcare provider for evaluation and possible dose adjustment is advisable.
Can meloxicam cause swelling in my ankles? Peripheral edema occurs in a minority of patients; if swelling becomes noticeable or painful, seek medical advice promptly.
Are there foods I must avoid while taking meloxicam? No specific foods are contraindicated, but taking the medication with a meal can help minimize stomach upset.
Will meloxicam interact with my blood pressure medication? NSAIDs can diminish the antihypertensive effect of certain drugs like ACE inhibitors or diuretics; monitor blood pressure regularly and discuss any changes with your clinician.
Is a topical meloxicam formulation as effective as oral tablets? Topical preparations deliver the drug directly to the affected area and may reduce systemic exposure, but they are generally less potent for severe joint inflammation compared with oral dosing.
What information should I provide my doctor when discussing meloxicam?
- Complete list of current medications, including over-the-counter drugs and supplements.
- History of gastrointestinal ulcers, bleeding, or cardiovascular disease.
- Any known allergies to NSAIDs or oxicams.
- Specific pain or inflammation targets and prior treatment responses.

Disclaimer

The information provided about meloxicam is for general knowledge only. It does not replace professional medical consultation or the official prescribing information for medications containing this ingredient. All treatment decisions, including dosing, formulation selection, and monitoring, should be made under the supervision of a qualified healthcare provider who can assess individual medical history, current medications, and specific health needs. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to medications containing meloxicam for individuals who may have limited availability through traditional pharmacies, insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication containing meloxicam.