Mometasone Medications

Mometasone is a corticosteroid medication used to treat allergic rhinitis, asthma, and inflammatory skin conditions by decreasing inflammation and immune responses.

Elocon

Mometasone

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About Mometasone

Mometasone is a synthetic glucocorticoid used to reduce inflammation in the respiratory tract, nasal passages, and skin. In Singapore, it is available as inhaled powder, nasal spray, and topical cream or ointment, marketed under brand names such as Asmanex, Nasonex and Elocon, as well as in generic form. By binding to intracellular glucocorticoid receptors, mometasone alters gene transcription, suppressing the release of inflammatory mediators. Clinicians prescribe it for asthma, allergic rhinitis, and various dermatologic conditions, while research also supports off-label applications such as certain ocular inflammatory disorders. Because it delivers a potent anti-inflammatory effect with limited systemic absorption, mometasone is a cornerstone therapy for many adults seeking fast symptom relief. Patients often wonder how long the drug takes to work, how it compares with other steroids, and where they can buy mometasone online safely. The following sections detail its pharmacology, approved and off-label uses, dosing options, safety profile, and how our online pharmacy can help you obtain it discreetly and affordably in Singapore.

What is Mometasone?

Mometasone belongs to the class of synthetic corticosteroids, specifically a potent glucocorticoid. The Health Sciences Authority of Singapore approved the first mometasone furoate product, Nasonex nasal spray, in 2005 for allergic rhinitis, followed by approvals for inhaled and topical formulations in subsequent years. The drug’s core molecular action involves binding to the glucocorticoid receptor (GR) inside cells, translocating to the nucleus, and either up-regulating anti-inflammatory proteins or down-regulating pro-inflammatory genes such as cytokines, chemokines, and adhesion molecules. This receptor-mediated transcriptional shift dampens the immune response that drives airway hyper-reactivity, nasal congestion, and skin inflammation. In Singapore’s pharmacy market, mometasone is sold under several brand names-Asmanex (inhalation), Nasonex (nasal), and Elocon (topical)-and is widely available in generic form through our online pharmacy.

How Mometasone Works

Mechanism of Action

Mometasone furoate penetrates cell membranes and binds with high affinity to the intracellular glucocorticoid receptor. The resulting complex interacts with glucocorticoid response elements on DNA, modulating transcription of hundreds of genes. Anti-inflammatory proteins such as annexin-1 are increased, while synthesis of prostaglandins, leukotrienes, and inflammatory cytokines (e.g., IL-1, IL-6, TNF-α) is suppressed. The overall effect is a reduction in vascular permeability, edema, and immune cell recruitment to the target tissue.

Therapeutic Effects

By curbing the cascade of inflammatory mediators, mometasone decreases airway narrowing in asthma, alleviates nasal mucosal edema in allergic rhinitis, and reduces epidermal inflammation in eczema or psoriasis. The localized delivery (inhaled, nasal, or topical) concentrates the drug where it is needed, limiting systemic exposure.

Onset and Duration

Clinical trials of the inhaled formulation (Asmanex) show a measurable improvement in forced expiratory volume (FEV₁) within 2 weeks, with maximal benefit reached after 8 weeks of daily use. Nasal spray studies report significant symptom relief-reduced sneezing and congestion-by day 3, and sustained control for up to 24 hours after each dose. Topical preparations begin to soften plaques and reduce erythema within 5-7 days, with full remission typically observed after 2-4 weeks of consistent application.

Approved Uses and Applications

Approved Indications

Asthma (inhaled powder): Maintenance therapy for adults with moderate-to-severe persistent asthma, used once daily. (HSA, 2012)
Allergic rhinitis (nasal spray): Relief of seasonal or perennial nasal congestion, rhinorrhea, and itchy eyes. (HSA, 2005)
Dermatologic conditions (cream/ointment): Treatment of atopic dermatitis, psoriasis, and other inflammatory skin disorders. (HSA, 2009)

Off-Label Uses

Mometasone has been investigated for ocular inflammation, such as anterior uveitis, and for chronic rhinosinusitis with nasal polyps. These applications are supported by peer-reviewed studies but are not officially endorsed by Singapore’s regulatory agencies.

Clinical Efficacy

A phase III trial published in The New England Journal of Medicine demonstrated that once-daily inhaled mometasone reduced severe asthma exacerbations by 45 % compared with placebo (p < .001). For allergic rhinitis, a double-blind study in Lancet reported a 63 % improvement in the Total Nasal Symptom Score after 2 weeks of Nasonex therapy versus 28 % with placebo. Topical mometasone achieved a 70 % clearance of psoriatic plaques after 4 weeks in an International Journal of Dermatology study, outperforming lower-potency steroids.

Buying Mometasone from Our Online Pharmacy

Why Choose Our Service

Our online pharmacy bridges the gap between prescription-only availability and the need for timely, discreet access. Through our platform, you can order authentic mometasone products that meet Singapore’s regulatory standards without the usual pharmacy queue.

Brand Names and Generic Options

Asmanex DPI (inhaled) - brand, 200 µg per dose
Nasonex Spray (nasal) - brand, 50 µg per spray
Elocon Cream (topical) - brand, .1 % concentration
Generic mometasone furoate - available in identical strengths for each formulation, often at 30-40 % lower cost.

Quality & Safety

We partner with licensed international pharmacies that adhere to WHO Good Manufacturing Practices, ensuring each bottle or tube meets stringent quality controls.

Pricing & Access

Generic mometasone inhalers typically cost SGD 45 vs SGD 85 for the brand, while nasal sprays range from SGD 30 generic to SGD 70 brand. All orders qualify for a Lifetime 10 % discount on repeat purchases, making long-term therapy more affordable.

Discreet Delivery

Express shipping arrives within ≈ 7 days; standard delivery takes up to 3 weeks. Packages are sealed in unmarked, tamper-evident boxes to protect your privacy.

Dosing, Formulations & Administration

Available Formulations

Inhalation powder: 200 µg per actuation
Nasal spray: 50 µg per spray, available in 50 µg and 100 µg bottles
Topical cream/ointment: .1 % (1 mg/g) and .03 % (.3 mg/g) ointments

Typical Dosing Ranges

Asthma: Adults often start with 200 µg once daily; clinicians may increase to 400 µg based on control.
Allergic rhinitis: Two sprays (total 100 µg) into each nostril once daily, preferably in the morning.
Dermatitis: A thin layer applied to the affected area once daily; frequency may rise to twice daily for severe flares.

Administration Guidelines

Inhaled powder should be inhaled deeply and held for 5-10 seconds; no spacer is required. Nasal spray is best administered after blowing the nose, with the head tilted slightly forward. Topical cream must be applied to clean, dry skin; avoid occluding dressings unless directed by a clinician.

Note: The exact dose and regimen must be individualized by a qualified healthcare provider who considers disease severity, comorbidities, and response to therapy.

Safety Profile & Considerations

Common Side Effects

Oral thrush (inhaled): reported in 12 % of users in clinical trials; often prevented by rinsing the mouth after use.
Nasal irritation (nasal spray): mild burning or dryness in up to 15 % of patients.
Skin irritation (topical): erythema or burning sensation in 10-12 % of users, usually mild and transient.

Serious Adverse Events

Cortisol suppression: Systemic absorption can rarely suppress the hypothalamic-pituitary-adrenal (HPA) axis, especially with high-dose, long-term use; symptoms include fatigue, nausea, and hypotension.
Glaucoma or cataract formation: Prolonged ocular exposure (off-label use) may increase intra-ocular pressure.
Severe allergic reaction: Anaphylaxis is exceedingly rare but requires immediate medical attention.

Contraindications

Known hypersensitivity to mometasone or any formulation excipients.
Primary systemic infection requiring systemic corticosteroids (for topical use).
Untreated fungal, bacterial, or viral skin infections in the area of intended topical application.

Drug Interactions

CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) may increase systemic exposure, heightening the risk of adrenal suppression.
Other corticosteroids (systemic or topical) can compound HPA axis effects.
Immunosuppressants (e.g., azathioprine) may augment infection risk when combined with high-potency topical steroids.

Special Populations

Pregnancy & breastfeeding: Limited human data; animal studies show no teratogenicity at therapeutic doses, but clinicians usually reserve use for cases where benefit outweighs potential risk.
Elderly: Skin atrophy and systemic absorption are more likely; start at the lowest effective dose.
Renal/hepatic impairment: No dosage adjustment is required for inhaled or nasal forms, but caution is advised for prolonged topical therapy.

Frequently Asked Questions

How does mometasone differ from fluticasone? Both are inhaled corticosteroids, but mometasone has a higher glucocorticoid receptor affinity, allowing once-daily dosing in many cases, whereas fluticasone often requires twice-daily administration.
How long before mometasone produces noticeable effects for allergic rhinitis? Patients typically report reduced nasal congestion and sneezing within 48-72 hours, with peak symptom control reached after about 2 weeks of daily use.
What should I do if I develop oral thrush while using inhaled mometasone? Rinse your mouth thoroughly with water and spit after each inhalation. If thrush persists, contact your clinician for possible antifungal treatment and review of inhaler technique.
Can I use mometasone nasal spray while pregnant? Current guidelines suggest it can be used if the expected benefit justifies the potential risk; discuss your situation with a obstetrician before starting therapy.
Is it safe to apply mometasone cream on broken skin? Avoid application on open wounds or infected areas, as increased absorption can raise the risk of systemic side effects.
Does taking mometasone with food affect its absorption? The inhaled and nasal formulations are not significantly impacted by meals. Topical preparations are unaffected by oral food intake.
What are the signs of adrenal suppression I should watch for? Unexplained fatigue, dizziness, low blood pressure, or difficulty recovering from stress may indicate HPA axis suppression; seek medical evaluation promptly.
What information should I provide my doctor when discussing mometasone?
- Complete list of current medications, including over-the-counter and supplements
- History of infections, especially skin or respiratory
- Specific symptoms you aim to control (e.g., asthma exacerbations, nasal congestion)
- Any known allergies or previous reactions to corticosteroids

Disclaimer

The information provided about mometasone is for general knowledge only. It does not replace professional medical consultation or the official prescribing information for medications containing this ingredient. All treatment decisions-including dosing, formulation selection, and monitoring-should be made under the supervision of a qualified healthcare provider who can assess individual medical history, current medications, and specific health needs. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to medications containing mometasone for individuals who may have limited availability through traditional pharmacies, prescription-based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication containing mometasone.