Buy Loxitane
Loxitane

$0.73
Category
Psychotic Disorders
Active Ingredient
Loxapine
Delivery
Airmail (14-21 days) | EMS trackable (5-9 days)
Prescription
Issued on site / Included
Availability
In Stock
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Loxitane Properties

Active Ingredients
Loxapine
Primary Category
Mental Health
Pharmacological Class
Typical Antipsychotic (sometimes considered atypical), Dibenzoxazepine
Minor Side Effects
Drowsiness , Dizziness , Dry mouth
Moderate Side Effects
Blurred vision , Constipation , Nasal congestion
Dosage Forms
Capsules, Oral Solution, Inhalation Powder
Administration Route
Oral
Mechanism of Action
Primarily blocks dopamine receptors in the brain. This action helps to reduce certain symptoms associated with schizophrenia, such as hallucinations and delusions.
Prescription Status
Rx
Patient Summary
An antipsychotic medication used to help manage the symptoms of schizophrenia.
Onset Time
Hours to days
Duration
About 12 hours
Storage Instructions
Store at room temperature, away from moisture
Age Restrictions
Use is typically for adults with schizophrenia
Pregnancy Use
Consult doctor before use during pregnancy or breastfeeding

About Loxitane

Generic Loxitane (Loxapine) is an oral antipsychotic tablet approved for the treatment of schizophrenia and other psychotic disorders in Singapore. As a member of the thioxanthene class, it works by balancing dopamine and serotonin activity in the brain, helping to reduce hallucinations, delusions, and disorganized thinking. The medication is available in 10 mg and 25 mg strengths and is prescribed by clinicians when a typical antipsychotic is deemed appropriate for a patient’s clinical profile. While its primary indication is psychosis, clinicians sometimes consider Loxitane for related conditions after weighing potential benefits against risks.

Table of Contents

What is Generic Loxitane (Loxapine)?

Generic Loxitane (Loxapine) is a prescription-only pill that belongs to the thioxanthene family of typical antipsychotics. It received regulatory approval from Singapore’s Health Sciences Authority and is marketed in tablet form for adult patients. The product is manufactured under strict quality standards and contains the active ingredient loxapine hydrochloride, the same molecule found in older brand-name formulations such as Loxapac. In Singapore, it is listed as a Schedule 4 medication, meaning a doctor’s prescription is required for dispensing.

How Loxitane Works

Loxapine exerts its therapeutic effect primarily by blocking dopamine D₂ receptors in the mesolimbic pathway, which dampens the excessive dopaminergic signaling that underlies psychotic symptoms. It also antagonizes serotonin 5-HT₂A receptors, contributing to mood stabilization and reducing the risk of certain extrapyramidal side effects. The drug is absorbed rapidly after oral administration, reaching peak plasma concentrations within 1-2 hours. It undergoes hepatic metabolism mainly via CYP1A2 and CYP3A4, producing inactive metabolites that are eliminated through the kidneys. The typical onset of antipsychotic action occurs within a few days, with full therapeutic benefits often observed after 2-4 weeks of consistent dosing.

Why Loxitane is Used for Mental Health Conditions

  • Schizophrenia: By reducing dopaminergic overactivity, Loxitane lessens positive symptoms such as hallucinations and delusions, helping patients regain functional capacity.
  • Acute Psychosis: The rapid absorption of the tablet form allows clinicians to manage sudden exacerbations effectively when oral therapy is feasible.
  • Adjunctive Therapy in Bipolar Disorder: Some clinicians use Loxitane off-label to control manic agitation when mood stabilizers alone are insufficient, leveraging its dopamine-blocking properties.
  • Treatment-Resistant Cases: For patients who do not respond adequately to newer atypical agents, Loxitane offers an alternative mechanism that may yield clinical improvement.

In each scenario, the drug’s mechanism aligns with the underlying neurobiology, making it a logical choice within treatment guidelines that prioritize symptom control and safety.

Off-Label and Investigational Uses of Loxitane

Evidence from small open-label studies and case series suggests that Loxitane may aid in managing severe agitation associated with dementia and in reducing impulsivity in borderline personality disorder. However, these uses have not received formal approval from the HSA. Off-label use should only be considered under the supervision of a qualified healthcare provider.

Is Loxitane Right for You?

Loxitane is most suitable for adults with a confirmed diagnosis of schizophrenia or acute psychosis who have not responded adequately to other antipsychotics. It can be prescribed to patients with stable liver function, as hepatic metabolism is a key pathway for clearance. Caution is advised for individuals with a history of cardiovascular disease, uncontrolled diabetes, or seizure disorders. Pregnant or breastfeeding women should only use Loxitane if the potential benefit outweighs the risk, after thorough discussion with their obstetrician. The medication is generally not recommended for children and adolescents because safety data in those age groups are limited.

Taking Loxitane Effectively

  • Timing: Take the tablet once daily, preferably in the evening, to align with its sedative properties and minimize daytime drowsiness.
  • Food Interactions: Loxitane can be taken with or without food; a consistent routine helps maintain stable plasma levels.
  • Missed Dose: If a dose is missed and it is less than 12 hours until the next scheduled dose, take the missed tablet promptly. Skip it if it is closer to the next dose to avoid double-dosing.
  • Travel: Carry a written prescription and keep tablets in their original packaging to comply with Singapore’s import regulations.
  • Alcohol and CNS Depressants: Limit alcohol consumption and avoid simultaneous use of other sedating agents, as additive CNS depression can increase fall risk.

Understanding Side Effects and How to Manage Them

  • Extrapyramidal Symptoms (EPS): Muscle stiffness, tremor, or restlessness may arise from dopamine blockade. Low-dose anticholinergic agents (e.g., benztropine) can alleviate mild EPS, while dose reduction is often effective for more severe cases.
  • Sedation: Drowsiness is common, especially during treatment initiation. Scheduling the dose in the evening and avoiding driving until the medication’s impact is known can mitigate safety concerns.
  • Weight Gain & Metabolic Changes: Monitor body weight, fasting glucose, and lipid profile regularly; lifestyle modifications and, if needed, referral to a dietitian are prudent.
  • Prolactin Elevation: Elevated prolactin can cause menstrual irregularities or galactorrhea. Periodic hormone assessments help detect this early; switching to a different antipsychotic may be considered if clinically significant.
  • Cardiovascular Effects: Orthostatic hypotension may lead to dizziness; advise patients to rise slowly from seated positions.

Serious adverse events such as neuroleptic malignant syndrome or severe cardiac arrhythmias are rare but require immediate medical attention. Patients should be instructed to seek emergency care if they experience high fever, rigid muscles, uncontrolled tremor, or chest pain.

Buying Loxitane from Our Online Pharmacy

Why Choose Our Service?

Our online pharmacy bridges the gap for patients who face limited local stock or insurance constraints, delivering Loxitane discreetly to your doorstep. By partnering with licensed international suppliers, we guarantee product authenticity while offering competitive pricing.

Quality & Safety

We work with accredited pharmacies that comply with WHO Good Distribution Practices, ensuring each tablet meets stringent potency and sterility standards before shipment.

Pricing & Access

Generic Loxitane offers a cost-effective alternative to older brand formulations. Patients can benefit from a Lifetime 10 % discount on all reorders, and bulk purchases further reduce out-of-pocket expenses.

Discreet Delivery

Orders are packaged in plain, tamper-evident containers. Express shipping typically arrives within 7 days, while the standard option reaches you in 3 weeks, both with full tracking.

Frequently Asked Questions

  • Is Loxitane safe for elderly patients? Loxitane can be used in older adults, but clinicians often start at the lower end of the dosing range (10 mg) and monitor closely for sedation, orthostatic hypotension, and EPS, which are more prevalent in this population.

  • Can I switch from an atypical antipsychotic to Loxitane? A gradual cross-titration is recommended to minimize withdrawal or rebound psychosis. Your prescriber will devise a schedule that reduces the atypical dose while introducing Loxitane at a low dose.

  • How long does it take to feel relief from psychotic symptoms? Initial improvements in agitation and hallucinations may appear within a few days, but noticeable stabilization of thought processes typically requires 2-4 weeks of consistent treatment.

  • What should I do if I experience severe tremors? Severe tremors may indicate EPS. Contact your healthcare provider promptly; they may add an anticholinergic medication or adjust the Loxitane dose.

  • Is it possible to use Loxitane for bipolar mania? While not approved for this indication in Singapore, some psychiatrists prescribe it off-label for acute manic episodes, especially when other mood stabilizers are insufficient. This decision must be made under specialist supervision.

  • Will Loxitane interact with my antidepressant? Loxitane’s metabolism via CYP1A2 and CYP3A4 can be affected by certain antidepressants (e.g., fluvoxamine, sertraline). A drug-interaction check is essential before co-prescribing.

  • Can I take Loxitane while pregnant? The medication is classified as Category C in Singapore; animal studies have shown some risk, and human data are limited. Use only if the therapeutic benefit outweighs potential fetal risks, after discussion with an obstetrician.

  • How should I store Loxitane tablets? Keep the tablets in their original container at room temperature, away from moisture and direct sunlight. Do not refrigerate or freeze.

  • What is the recommended duration of treatment? Schizophrenia is typically a chronic condition; many patients continue Loxitane long-term, with periodic assessments to evaluate efficacy, side-effects, and the possibility of dose reduction.

  • Are there any dietary restrictions? No specific foods need to be avoided, but maintaining a balanced diet supports overall metabolic health and can mitigate weight-gain associated with antipsychotic therapy.

Glossary

D₂ Receptor
A dopamine receptor subtype whose overactivity is linked to psychotic symptoms; antagonism reduces hallucinations and delusions.
Extrapyramidal Symptoms (EPS)
Movement disorders such as tremor, rigidity, and bradykinesia that arise from dopamine blockade in the motor pathways.
Thioxanthene
A class of typical antipsychotics, chemically related to phenothiazines, characterized by a sulfur-containing tricyclic structure.

Disclaimer

The information provided about Loxitane is for general knowledge only. It does not replace professional medical consultation. All treatment decisions, including those regarding off-label use, should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Loxitane for individuals who may have limited availability through traditional pharmacies, prescription-based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.

External Resources about Loxitane

Information Prepared By

Nawin Kittisak
Platform Manager & Website Administrator
Vikneswaran V Paranjothy
General Practitioner