Buy Stromectol
Stromectol
Stromectol Properties
About Stromectol
Stromectol (generic Ivermectin) is an antiparasitic medication commonly prescribed for a variety of infections caused by worms, mites and lice. In Singapore it is available only with a prescription and is marketed in tablet strengths of 3 mg, 6 mg and 12 mg. The drug works by targeting the nervous system of invertebrates, leading to paralysis and death of the parasite. While its primary indications are well-established, clinicians sometimes consider off-label uses based on emerging research. This article explains how Stromectol functions, why it is chosen for specific infections, and practical tips for safe use.
What is Generic Stromectol (Ivermectin)?
Generic Stromectol (Ivermectin) belongs to the macrocyclic lactone class of antiparasitic agents. It received registration with Singapore’s Health Sciences Authority (HSA) for oral treatment of onchocerciasis, strongyloidiasis, scabies, and head-lice infestations. The tablets are formulated for oral ingestion and come in three dose strengths-3 mg, 6 mg, and 12 mg-allowing clinicians to tailor the regimen to body weight and the specific infection. The medication is prescription-only, reflecting its potent pharmacology and the need for professional dosing guidance.
How Stromectol Works
Ivermectin binds selectively to glutamate-gated chloride channels that are present on the nerve and muscle cells of many invertebrates but are absent in humans. This binding increases the permeability of the cell membrane to chloride ions, causing hyperpolarization of the nerve or muscle cell. The resulting loss of neuronal firing leads to paralysis of the parasite, which is then expelled or destroyed by the host’s immune system.
Pharmacokinetic studies show that oral tablets are absorbed rapidly, reaching peak plasma concentrations within 4 hours. Metabolism occurs primarily in the liver via CYP3A4, and the drug’s half-life ranges from 12 to 36 hours, depending on the dose and individual factors. Because humans lack the target chloride channels, systemic toxicity is low when the drug is used at approved doses.
Why Stromectol Is Used for Infections
- Onchocerciasis (river blindness): The drug’s ability to paralyze microfilariae in the skin and eyes reduces inflammation and prevents ocular damage. WHO recommends a single dose of 150 µg/kg, making it a cornerstone of community-based eradication programs.
- Strongyloidiasis: Ivermectin’s penetration into intestinal tissues eradicates the larval stages that other anthelmintics miss, leading to cure rates above 90 % in clinical trials.
- Scabies: By disrupting the neuromuscular function of Sarcoptes scabiei mites, a single oral dose of 200 µg/kg often clears infestation, offering an alternative when topical therapy fails or is impractical.
- Pediculosis (head lice): A single 200 µg/kg dose eliminates lice and nits, and the oral route avoids the scratching and resistance issues linked to over-the-counter shampoos.
In each case, the drug’s mechanism directly targets a physiological process essential for parasite survival, which explains its high efficacy and why treatment guidelines place ivermectin as first-line therapy for these conditions.
Off-Label and Investigational Uses of Stromectol
Research has explored ivermectin for viral infections, most notably COVID-19. Small-scale trials and observational studies suggested a possible reduction in viral replication, but larger randomized controlled trials have not confirmed a clinically significant benefit. Consequently, the HSA has not authorized ivermectin for COVID-19, and its use for this purpose should only occur under the supervision of a qualified healthcare provider.
Other investigational areas include certain dermatological conditions such as rosacea, where anti-inflammatory properties have been observed in pilot studies. These uses remain experimental and are not endorsed in official treatment guidelines.
Off-label use should only be considered under the supervision of a qualified healthcare provider.
Is Stromectol Right for You?
Stromectol is appropriate for adults and children weighing 15 kg or more who have a confirmed parasitic infection that responds to ivermectin. Patients with severe hepatic impairment may require dose-adjustment, as the drug is metabolized in the liver. While pregnancy is not an absolute contraindication, the HSA advises that ivermectin be prescribed only when the potential benefit outweighs any unknown risks to the fetus.
Elderly patients generally tolerate the medication well, but clinicians monitor for drug-drug interactions, especially with other CYP3A4 substrates such as certain antiretrovirals or macrolide antibiotics. Renal dysfunction does not markedly affect ivermectin clearance, so dose reduction is rarely needed for kidney disease.
Taking Stromectol Effectively
- Timing: Take the tablet on an empty stomach, preferably with a glass of water, to maximize absorption.
- Food interactions: High-fat meals can modestly increase plasma concentrations; consistent intake relative to meals helps maintain stable exposure.
- Missed dose: If a dose is missed, take it as soon as remembered unless the next scheduled dose is within 12 hours; in that case, skip the missed dose and continue the regular schedule. Do not double-dose.
- Travel tips: When traveling to endemic regions, carry a written prescription and sufficient quantity of tablets, as local pharmacies may have limited stock.
Adhering to the prescribed regimen and completing the full course-even if symptoms improve early-ensures eradication of the parasite and reduces the chance of relapse.
Understanding Side Effects and How to Manage Them
Common adverse effects such as mild nausea, diarrhea, dizziness, and pruritus arise from ivermectin’s modest activity on human GABA-gated chloride channels at high concentrations. These symptoms are usually transient and resolve without intervention.
- Nausea or stomach upset: Taking the tablet with a small amount of food can lessen discomfort.
- Dizziness: Sit or lie down until the sensation passes; avoid operating heavy machinery until steady.
Rare but serious reactions include severe skin rash, visual disturbances, or signs of central nervous system toxicity (e.g., seizures). These events are linked to excessive plasma levels, often due to overdose or drug interactions. Seek immediate medical attention if any of these occur.
Buying Stromectol from Our Online Pharmacy
Why Choose Our Service?
Our online pharmacy simplifies access to prescription-only medications like Stromectol, especially for patients facing limited local stock or mobility challenges. By verifying prescriptions electronically, we maintain the same safety standards as brick-and-mortar pharmacies while delivering the medicine directly to your door.
Quality & Safety
We partner-with licensed international pharmacies that operate under stringent regulatory frameworks recognized by the World Health Organization. Every batch of Stromectol undergoes third-party testing to confirm potency and purity before shipment.
Pricing & Access
Because Stromectol is available as a generic, we can offer competitive pricing that often undercuts conventional retail rates. In addition, we provide a Lifetime 10 % discount on all reorders, making long-term management of chronic parasitic conditions more affordable.
Discreet Delivery
Orders are packaged in neutral, tamper-evident containers. Express shipping typically arrives in 7 days, while standard delivery is completed within 3 weeks, all with full confidentiality.
Frequently Asked Questions
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How quickly will I feel relief after taking Stromectol? Most patients notice a reduction in itching or rash within 24 to 48 hours as the parasites are immobilized, though the complete cure may take several days depending on the infection.
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Can I take Stromectol with other medications? Ivermectin is metabolized by CYP3A4, so drugs that strongly induce or inhibit this enzyme (e.g., rifampicin, ketoconazole) can alter its levels. Always inform your clinician about concurrent medicines.
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Is it safe to use Stromectol for scabies in children under 15 kg? The drug is not recommended for infants or very low-weight children because the dose-calculations become less reliable and safety data are limited.
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What distinguishes Stromectol from topical scabicides? Oral ivermectin reaches mites residing in deeper skin layers that topical agents may miss, providing a systemic approach that often requires only a single dose.
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Will I need a follow-up test after treatment? For onchocerciasis and strongyloidiasis, a repeat stool or skin snip examination after 2 weeks confirms eradication. Scabies and lice typically resolve clinically without lab confirmation.
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Why do some patients experience a temporary worsening of symptoms? As parasites die, their antigens are released, potentially triggering a short-term inflammatory response. This “Mazzotti reaction” is self-limited and can be managed with antihistamines.
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Can I purchase Stromectol without a prescription through the pharmacy? No. Our service complies with Singaporean regulations, requiring a valid prescription from a licensed prescriber before dispensing any medication.
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How does ivermectin differ from other antiparasitics like albendazole? Ivermectin targets chloride channels, while albendazole inhibits microtubule synthesis. The differing mechanisms make each drug more suitable for specific parasites, and sometimes they are used together for synergistic effect.
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Is resistance to Stromectol a concern? Resistance has been documented in some veterinary parasites, but human clinical resistance remains rare. Proper dosing and adherence to treatment courses help minimize this risk.
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What should I do if I accidentally take a higher dose than prescribed? Contact emergency medical services immediately. Overdose can lead to neurological toxicity, which requires prompt evaluation.
Glossary
- Glutamate-gated chloride channel
- A protein channel in invertebrate nerve cells that, when opened by ivermectin, allows chloride ions to flow in, causing hyperpolarization and paralysis.
- Mazzotti reaction
- An inflammatory response that may occur after rapid death of filarial parasites, characterized by fever, itching, and rash.
- CYP3A4
- A liver enzyme that metabolizes many drugs, including ivermectin; inhibitors or inducers of this enzyme can alter ivermectin levels.
- Pharmacokinetics
- The study of how a drug is absorbed, distributed, metabolized, and excreted by the body.
- Prescription-only medicine
- A medication that can be dispensed only with a valid prescription from a qualified healthcare professional.
Disclaimer
The information provided about Stromectol is for general knowledge only. It does not replace professional medical consultation. All treatment decisions, including those regarding off-label use, should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Stromectol for individuals who may have limited availability through traditional pharmacies, prescription-based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.
