Buy Tiova Rotacap
Tiova Rotacap

$106.65
Active Ingredient
Delivery
Airmail (14-21 days) | EMS trackable (5-9 days)
Prescription
Issued on site / Included
Availability
In Stock
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Tiova Rotacap Properties

Active Ingredients
Primary Category
Pharmacological Class
Long-Acting Anticholinergic Bronchodilator
Indications
Minor Side Effects
Dosage Forms
Inhalation Powder
Administration Route
Inhalation
Mechanism of Action
A long-acting anticholinergic medicine that helps to open airways in the lungs, making it easier to breathe. It relaxes muscles around the airways.
Prescription Status
Rx
Manufacturer
Cipla
Patient Summary
Used to manage symptoms of COPD (chronic obstructive pulmonary disease) by helping to keep airways open and improve breathing over time.
Onset Time
Within 30 minutes
Duration
Up to 24 hours
Storage Instructions
Store in a cool, dry place, keep blister sealed until use
Age Restrictions
Not recommended for children under 18
Pregnancy Use
Consult doctor before use during pregnancy or breastfeeding
Alternative Drugs

About Tiova Rotacap

Generic Tiova Rotacap (Tiotropium Bromide) is a once-daily inhalation therapy designed to improve breathing in adults with chronic obstructive pulmonary disease (COPD) and, in some regions, as an add-on for asthma. The active ingredient, tiotropium bromide, belongs to the anticholinergic class of bronchodilators and works by relaxing airway smooth muscle, thereby easing airflow obstruction. Approved by Singapore’s Health Sciences Authority for maintenance treatment of COPD, this product offers a convenient bottle-pack form delivering 15 capsules that can be used with a standard HandiHaler® device. Understanding how it functions, its role in respiratory care, and practical tips for safe use can help patients achieve better breath control and a higher quality of life.

What is Generic Tiova Rotacap (Tiotropium Bromide)?

Generic Tiova Rotacap (Tiotropium Bromide) is a prescription-only bronchodilator formulated as a dry-powder inhalation capsule. Classified as a long-acting muscarinic antagonist (LAMA), it received regulatory approval in Singapore for the long-term management of COPD, reflecting extensive clinical testing that demonstrated sustained lung-function improvement and reduced exacerbations. Although marketed under the Tiova brand, the formulation contains the same active molecule as well-known products such as Spiriva®, ensuring bioequivalence in terms of dose delivery and therapeutic effect. The product is supplied in a bottle of 15 capsules, each intended for a single inhalation session.

How Tiova Rotacap Works

Tiotropium bromide blocks muscarinic M₃ receptors on airway smooth muscle. Acetylcholine, a neurotransmitter released from parasympathetic nerves, normally binds these receptors, triggering calcium influx and muscle constriction. By occupying the receptor sites, tiotropium prevents this cascade, leading to sustained bronchodilation for up to 24 hours after a single inhalation. Pharmacokinetically, the drug exhibits minimal systemic absorption; about 10 % reaches the bloodstream, where it is slowly eliminated via renal excretion with a half-life of roughly 5 days, allowing once-daily dosing. Because the effect is localized to the lungs, systemic side effects are uncommon, and the drug’s onset of action occurs within 30 minutes, providing relatively rapid symptom relief while maintaining long-term airway patency.

Why Tiova Rotacap is Used for Respiratory Care Conditions

  • Chronic Obstructive Pulmonary Disease (COPD) - The drug’s anticholinergic action directly counteracts the cholinergic dominance that characterises COPD-related airway narrowing. Clinical trials, such as the UPLIFT study, showed a 15 % reduction in exacerbation risk and a mean improvement of .12 L in FEV₁ over 4 years. Guidelines from the Global Initiative for Chronic Obstructive Lung Disease (GOLD) endorse LAMA therapy as a first-line maintenance option for moderate-to-severe disease.
  • Asthma (add-on therapy) - In several peer-reviewed investigations, tiotropium added to inhaled corticosteroids improved lung function and reduced oral-steroid bursts in patients with uncontrolled asthma. While not a primary indication in Singapore, the evidence supports off-label use under specialist supervision, particularly for adults with a mixed COPD-asthma phenotype.
  • Exercise-induced bronchoconstriction - Limited data indicate that a single dose before exertion can blunt the acute decline in airflow, offering an alternative for athletes who experience bronchospasm despite standard reliever inhalers.

Compared with short-acting anticholinergics, tiotropium’s longer receptor residence time reduces dosing frequency and improves adherence. Within its class, it offers a more favourable safety profile than some β₂-agonists, especially concerning tachycardia and tremor.

Off-Label and Investigational Uses of Tiova Rotacap

Evidence from randomized controlled trials suggests potential benefits of tiotropium bromide in chronic rhinosinusitis and in reducing cough associated with gastro-oesophageal reflux disease, though these indications have not been approved by Singapore’s regulatory authority. Off-label use should only be considered under the supervision of a qualified healthcare provider, and patients must be informed that efficacy-and-safety data remain limited in these contexts.

Is Tiova Rotacap Right for You?

Tiova Rotacap is most suitable for adults with a confirmed diagnosis of COPD who require consistent bronchodilation and seek once-daily convenience. Patients with severe renal impairment may need dose adjustment, as reduced clearance can increase systemic exposure. Pregnancy and lactation data are insufficient; the medication should be avoided unless the potential benefit justifies the risk. Elderly individuals often experience better adherence with a single-dose regimen, but clinicians should verify inhaler technique regularly to ensure optimal drug deposition. Those with a known hypersensitivity to tiotropium or other anticholinergics should not use this product.

Taking Tiova Rotacap Effectively

  1. Preparation - Open the bottle, remove a capsule, and place it upright in the HandiHaler® chamber. Do not crush or ingest the capsule.
  2. Inhalation - Exhale fully, seal your lips around the mouthpiece, and press the capsule piercer. Inhale rapidly and deeply, then hold your breath for 10 seconds to allow maximum drug deposition.
  3. Timing - Take the capsule at the same time each day, preferably in the morning, to maintain steady plasma levels.
  4. Food and Drink - Tiotropium’s absorption is not affected by meals, but avoid drinking water immediately after inhalation to prevent capsule residue from being washed away.
  5. Missed Dose - If a dose is missed, take it as soon as remembered unless it is within 12 hours of the next scheduled dose; in that case, skip the missed dose and resume the regular schedule.
  6. Travel - The sealed bottle protects capsules from humidity; keep it in a cool, dry place and carry it as part of your medication kit to ensure uninterrupted therapy.

Understanding Side Effects and How to Manage Them

Because tiotropium acts locally on airway receptors, most adverse events are mild and related to its anticholinergic properties. Dry mouth occurs as the drug reduces salivary secretion; sipping water or using sugar-free lozenges can alleviate discomfort. Throat irritation often results from the powder particles contacting the mucosa; proper inhalation technique-slow, deep breaths-minimises this effect. Less common but clinically relevant side effects include urinary retention and constipation due to systemic muscarinic blockade; patients with prostate enlargement should monitor symptoms and report worsening. Serious events such as angio-edema or paradoxical bronchospasm are rare but require immediate medical attention. If any sign of allergic reaction-rash, swelling, or difficulty breathing-develops, discontinue use and seek urgent care.

Buying Tiova Rotacap from Our Online Pharmacy

Purchasing Tiova Rotacap through our online pharmacy offers a discreet, cost-effective pathway to obtain a medication that may be limited in brick-and-mortar outlets.

Why Choose Our Service?

Our platform connects you with licensed international suppliers that meet Singapore’s regulatory standards, ensuring that every capsule you receive is authentic and sourced from reputable manufacturers. We understand the challenges of chronic respiratory disease management and strive to make maintenance therapy accessible without compromising safety.

Quality & Safety

All batches are shipped under licensed international pharmacy agreements and are verified against WHO-GMP criteria. Each order includes a certificate of analysis, and our pharmacists conduct a final quality check before dispatch.

Pricing & Access

By sourcing generics directly, we can offer Tiova Rotacap at up to 40 % lower than typical retail pharmacy prices. Returning customers enjoy a lifetime 10 % discount on all reorders, and bulk purchases of multiple bottles are eligible for additional savings.

Discreet Delivery

Orders are packaged in neutral, tamper-evident boxes to protect privacy. Standard shipping reaches most Singapore addresses within 3 weeks, while our express option delivers in approximately 7 days, both with tracking enabled for peace of mind.

Frequently Asked Questions

  • How quickly will I notice improvement after starting Tiova Rotacap? Most patients report a noticeable reduction in breathlessness within the first few days, with full lung-function benefits solidifying after about two weeks of consistent use.

  • Can I use Tiova Rotacap together with a rescue inhaler? Yes. Tiova Rotacap is a maintenance therapy and does not replace short-acting bronchodilators. If you experience sudden worsening of symptoms, a rescue inhaler remains the appropriate immediate treatment.

  • Is there any risk of tolerance developing over time? Current evidence suggests that tolerance to LAMA therapy is uncommon because the drug binds irreversibly to muscarinic receptors, maintaining efficacy throughout long-term treatment.

  • What should I do if I accidentally swallow a capsule? Swallowing a capsule is unlikely to cause systemic toxicity, but you should contact a healthcare professional for guidance and monitor for any unexpected symptoms.

  • Do I need a special inhaler for Tiova Rotacap? The capsule is designed for use with the HandiHaler® device, which is widely available at pharmacies. If you do not own one, many suppliers include a compatible inhaler with the first bottle.

  • Will using Tiova Rotacap affect my ability to drive or operate machinery? Because systemic anticholinergic effects are minimal, most patients do not experience impairments. However, if you notice dizziness or visual changes, refrain from operating vehicles until symptoms resolve.

  • Can I switch from a brand LAMA to Tiova Rotacap without a doctor’s visit? Switching inhaled therapies should be overseen by a clinician to ensure appropriate dosing and technique, even when the products are bioequivalent.

  • Are there any dietary restrictions while on Tiova Rotacap? No specific food interactions have been identified. Maintaining a balanced diet supports overall respiratory health, but you may wish to limit excessive caffeine if you are prone to heart-rate fluctuations.

  • How does Tiova Rotacap compare with long-acting β₂-agonists? LAMAs like tiotropium target the cholinergic pathway, whereas LABAs stimulate β₂-receptors. Both improve airflow, but LAMAs have a lower risk of tachycardia and are often preferred for patients with cardiovascular concerns.

  • Is Tiova Rotacap covered by Singapore’s Medisave or insurance schemes? Coverage varies by provider; some private insurers include LAMA therapy under chronic disease benefits, while Medisave may not reimburse inhaled medications directly. Check with your insurer for specifics.

Glossary

Muscarinic M₃ receptor
A subtype of acetylcholine receptor located on airway smooth muscle; its activation causes bronchoconstriction, which tiotropium antagonises.
Long-acting muscarinic antagonist (LAMA)
A class of bronchodilators that provides sustained airway relaxation for up to 24 hours, reducing the need for multiple daily doses.
FEV₁ (Forced Expiratory - Volume in 1 second)
A spirometric measure of how much air a person can exhale forcefully in one second; improvements indicate better lung function.
HandiHaler®
A portable dry-powder inhaler device specifically engineered to pierce and disperse tiotropium capsules for optimal lung delivery.
Off-label use
Prescription of a medication for an indication, age group, or dosage not approved by the local regulatory authority.

Disclaimer

The information provided about Tiova Rotacap is for general knowledge only and does not replace professional medical consultation. All treatment decisions, including those regarding off-label use, should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Tiova Rotacap for individuals who may have limited availability through traditional pharmacies, prescription-based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.

External Resources about Tiova Rotacap


Information Prepared By

Nawin Kittisak
Vikneswaran V Paranjothy