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Precose

Generic Precose (acarbose) is an oral medication used to improve blood-glucose control in adults with type 2 diabetes. It belongs to the class of α-glucosidase inhibitors, agents that act locally in the gut to slow carbohydrate digestion. In Singapore, the drug is available by prescription in 25 mg and 50 mg tablet strengths. While its primary purpose is to blunt post-prandial glucose spikes, clinicians may also consider it when other oral agents are insufficient or not tolerated.

What is Generic Precose (acarbose)?

Generic Precose (acarbose) is a synthetic analogue of a natural bacterial product that inhibits brush-border α-glucosidases in the small intestine. The medication received regulatory approval from the Health Sciences Authority (HSA) of Singapore in the early -s and is listed in the national formulary for type 2 diabetes management. It is classified as a prescription-only medicine (POM) and is supplied in tablet form (25 mg and 50 mg). Because acarbose is minimally absorbed (<2 % of the dose), systemic exposure is low, which contributes to its safety profile.

How Precose Works

Acarbose binds competitively to the active sites of α-glucosidases-enzymes responsible for the final step of carbohydrate breakdown into absorbable monosaccharides. By delaying the hydrolysis of disaccharides and oligosaccharides, the drug postpones glucose absorption for 2-4 hours after a meal. This results in a lower and more gradual rise in post-prandial plasma glucose, reducing the overallcaemic load.

Pharmacokinetic data show that most of the dose remains in the gastrointestinal lumen, where it exerts its effect. The small fraction that is absorbed undergoes limited hepatic metabolism and is eliminated unchanged in the feces. The onset of action occurs within 30 minutes of ingestion, and the effect persists for the duration of the meal. Because the drug works locally, it does not influence fasting glucose or insulin secretion directly, making it particularly useful for patients whose primary challenge is post-prandial hyperglycaemia.

Why Precose is Used for Diabetes Conditions

• Post-prandial glucose control - By attenuating the rapid rise in glucose after meals, acarbose helps patients achieve target 2-hour post-prandial values recommended by the Singapore Clinical Practice Guidelines for Diabetes.
• Complementary to other agents - When used together with metformin, sulfonylureas, or DPP-4 inhibitors, acarbose adds an independent mechanism that can bring HbA1c down an additional .5-1. %.
• Weight-neutral profile - Unlike some insulin-secretagogues, acarbose does not cause weight gain; in some studies modest weight loss was observed, likely due to reduced caloric absorption.
• Reduced cardiovascular risk markers - Long-term studies have linked better post-prandial control with lower incidences of microvascular complications, supporting acarbose’s role in comprehensive risk management.
• First-line or add-on option - The HSA guidelines list α-glucosidase inhibitors as a secondary oral option after metformin, especially for patients with marked post-prandial excursions or intolerance to other classes.

Is Precose Right for You?

Precose is most appropriate for adults with type 2 diabetes who experience significant post-prandial glucose spikes despite metformin or lifestyle measures. It can be considered in patients who prefer a medication that does not promote weight gain and who have normal renal and hepatic function, as severe impairment can increase gastrointestinal side effects. Pregnant or lactating women should only use acarbose if the potential benefit outweighs the risk, and it is generally avoided in children because safety data are limited. As with any prescription drug, the decision to start Precose must be made in consultation with a qualified healthcare professional who can assess comorbidities, concomitant medications, and individual treatment goals.

Taking Precose Effectively

• Timing - Take each tablet with the first bite of a carbohydrate-containing meal; if a meal is missed, skip the dose.
• Food interactions - Because the drug works in the gut, the carbohydrate content of the meal influences its efficacy. A balanced meal with complex carbs maximises the glucose-lowering effect.
• Dose titration - Initiate therapy with 25 mg three times daily. If tolerated, increase to 50 mg three times daily after 2-4 weeks to achieve optimal control.
• Missed dose - If a dose is forgotten and the next meal is still >30 minutes away, take the missed tablet with that meal. Do not double-dose.
• Travel tips - Carry tablets in the original container to avoid confusion with other pills; a small, portable pill organizer works well for multiple daily doses.

Understanding Side Effects and How to Manage Them

The most common adverse events are gastrointestinal, reflecting acarbose’s local action:

• Flatulence and abdominal distension - Produced by bacterial fermentation of undigested carbohydrates. Reducing the amount of simple sugars in the diet and starting with the lowest dose can mitigate these symptoms.
• Diarrhoea - Occurs when unabsorbed carbs reach the colon. If diarrhoea is severe, temporarily reduce the dose to 25 mg three times daily until tolerance improves.
• Abdominal pain - Usually mild; advise patients to take the tablet with a full glass of water and to avoid very high-fat meals that can exacerbate discomfort.

Serious liver enzyme elevations have been reported rarely. Routine monitoring of hepatic function is recommended at baseline and periodically thereafter, especially in patients with pre-existing liver disease. Prompt medical attention is warranted if patients experience persistent jaundice, dark urine, or severe abdominal pain.

Buying Precose from Our Online Pharmacy

Why Choose Our Service?

Our online pharmacy bridges the gap between prescription access and convenient delivery, ensuring that patients in Singapore can obtain Precose without unnecessary delays. By leveraging licensed supply chains, we maintain a steady stock of both 25 mg and 50 mg tablets, allowing you to adhere to the dosing schedule prescribed by your clinician.

Quality & Safety

We partner with internationally accredited pharmaceutical distributors that comply with WHO Good Manufacturing Practice (GMP) standards. Each batch of Precose is verified for potency and purity before shipment, and all packaging meets the stringent requirements set by Singapore’s Health Sciences Authority.

Pricing & Access

Because acarbose is available as a generic, our pharmacy offers it at a price markedly lower than branded alternatives. Regular customers benefit from a 10 % discount on all reorders, and bulk purchases (e.g., a three-month supply) receive additional savings. Transparent pricing is displayed before checkout, and there are no hidden fees.

Discreet Delivery

Orders are dispatched in unmarked, tamper-evident parcels. Standard shipping arrives within 7 days, while our express option delivers in 3 days. All deliveries are made to the address you specify, with the option of a concealed package label for added privacy.

Frequently Asked Questions

• What should I do if I experience severe diarrhoea while taking Precose? Reduce the dose to the lowest tolerated level and contact your healthcare provider. Persistent or bloody diarrhoea warrants immediate medical evaluation.

• Can Precose be used together with insulin? Yes, acarbose can be combined with insulin; however, dose adjustments of insulin may be necessary to avoid hypoglycaemia, especially after meals.

• Is there a need to monitor blood glucose more frequently when starting Precose? Monitoring post-prandial glucose 1-2 hours after meals for the first two weeks helps assess the drug’s effect and guides dose titration.

• Why does Precose cause flatulence, and can dietary changes help? The drug leaves undigested carbohydrates to be fermented by gut bacteria, producing gas. Reducing intake of simple sugars and increasing fiber can lessen this side effect.

• Are there any drug-food interactions I should be aware of? Precose does not interact with most foods, but high-fat meals can delay its onset. It is advisable to take the tablet with the start of a carbohydrate-rich meal rather than a fatty one.

• How does Precose compare to other oral hypoglycaemic agents? Unlike metformin or sulfonylureas, acarbose works locally in the intestine and does not affect insulin secretion or hepatic glucose production. Its primary is the reduction of post-prandial glucose excursions.

• Can I take Precose if I have mild renal impairment? Mild to moderate renal dysfunction does not significantly alter acarbose exposure, but clinicians usually start at the lowest dose and monitor tolerance.

• Is Precose safe for elderly patients? Elderly individuals may be more prone to gastrointestinal side effects; a cautious titration approach is recommended.

• What happens if I forget a dose? If the next meal is still at least 30 minutes away, take the missed tablet with that meal. Do not double the dose to compensate for the missed one.

• Does Precose affect liver enzymes? Rarely, acarbose can cause transient elevations in liver transaminases. Baseline liver function tests and periodic monitoring are advised for patients with existing liver disease.

• Can I purchase Precose without a prescription through your platform? No. Precose is a prescription-only medication, and we require a valid prescription from a licensed Singapore-based healthcare provider before dispensing.

Glossary

α-Glucosidase

An enzyme located on the brush border of the small intestine that catalyzes the final step of carbohydrate digestion, converting disaccharides into absorbable monosaccharides.

Post-prandial glucose

The concentration of glucose in the bloodstream measured after a meal, typically 1-2 hours post-ingestion.

GMP (Good Manufacturing Practice)

International quality standards that ensure pharmaceutical products are consistently produced and controlled according to established guidelines.

HbA1c

Glycated haemoglobin, a laboratory measure reflecting average blood glucose levels over the previous two to three months.

Disclaimer

The information provided about Precose is for general knowledge only and does not replace professional medical consultation. All treatment decisions, including those regarding off-label use, should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Precose for individuals who may have limited availability through traditional pharmacies, prescription-based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.

External Resources about Precose

• Precose Advanced Patient Information - Drugs.com
• PRECOSE® (acarbose tablets) - Food and Drug Administration
• Precose, (acarbose) dosing, indications, interactions, adverse effects, and more
• Acarbose (Precose): Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD
• DailyMed - PRECOSE- acarbose tablet