Buy Prometrium
Prometrium
Prometrium Properties
About Prometrium
Generic Prometrium (Progesterone) is a prescription medication commonly used to support women’s health, particularly in hormone replacement therapy, menstrual disorders, and assisted reproductive treatments. Containing micronised progesterone, the pill formulation (available in 100 mg and 200 mg strengths) mimics the body’s natural hormone, helping to restore hormonal balance during the luteal phase, menopause, or after ovulation-inducing procedures. In Singapore, it is approved for these indications and is prescribed by clinicians to address progesterone deficiency and related symptoms. While the brand name is Prometrium, the active ingredient is identical to compounded progesterone, offering a reliable option for patients seeking hormone therapy under medical supervision.
What is Generic Prometrium (Progesterone)?
Generic Prometrium (Progesterone) belongs to the class of progestogens, synthetic analogues of the natural hormone progesterone. It received approval from the Health Sciences Authority (HSA) in Singapore as a prescription-only medication for luteal phase support, hormone replacement therapy, and treatment of menstrual-related conditions. The product is delivered as a micronised oral tablet, which enhances absorption compared with non-micronised forms, ensuring consistent plasma levels that closely resemble endogenous progesterone.
How Prometrium Works
Prometrium’s active ingredient, progesterone, binds to progesterone receptors in target tissues such as the uterus, breast, and brain. By activating these receptors, it prepares the endometrium for implantation, stabilises the uterine lining, and counteracts the proliferative effects of estrogen. The micronised particles dissolve rapidly in the gastrointestinal tract, allowing absorption via the lymphatic system and bypassing extensive first-pass hepatic metabolism. Peak serum concentrations are reached within 1-2 hours after oral intake, and the hormone’s half-life of roughly 10 hours supports once- or twice-daily dosing to maintain steady levels throughout the therapeutic window.
Why Prometrium is Used for Women’s Health, Sexual Health, Hormone Replacement Conditions
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Luteal-phase support in assisted reproduction Progesterone stabilises the endometrial lining, creating a receptive environment for embryo implantation. Clinical guidelines place it as a first-line adjunct after ovulation induction.
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Hormone replacement therapy (HRT) for menopause When combined with estrogen, progesterone prevents endometrial hyperplasia, reducing the risk of uterine cancer. It is recommended for women with an intact uterus requiring cyclical or continuous HRT.
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Management of irregular menstrual cycles or amenorrhoea By mimicking the natural luteal surge, Prometrium restores regular shedding of the endometrium, alleviating breakthrough bleeding.
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Treatment of endometriosis-related pain Progesterone induces decidualisation of ectopic endometrial tissue, thereby reducing inflammatory activity.
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Prevention of preterm birth in high-risk pregnancies Evidence indicates that progesterone supplementation can lower the incidence of preterm delivery in women with a short cervix.
In each scenario, the drug’s mechanism directly addresses the underlying hormonal deficiency or imbalance, positioning it as a cornerstone therapy within contemporary women's-health protocols.
Off-Label and Investigational Uses of Prometrium
Current peer-reviewed studies have explored progesterone for neuroprotective effects in traumatic brain injury and for mood stabilisation in perimenopausal depression. These investigations remain experimental, and the medication is not approved for such indications in Singapore. Off-label use should only be considered under the supervision of a qualified healthcare provider.
Is Prometrium Right for You?
Prometrium is suitable for adult women who require supplemental progesterone, particularly those undergoing fertility treatment, experiencing menopausal symptoms, or needing luteal support. It is generally well-tolerated in patients with normal hepatic and renal function. Caution is advised for individuals with a history of thromboembolic disease, hormone-sensitive cancers, or uncontrolled hypertension. Pregnant women should only use it when prescribed for specific obstetric indications, and breastfeeding mothers should discuss potential effects with their clinician.
Taking Prometrium Effectively
- Timing: Take the tablet with food or a light snack to improve absorption and reduce gastrointestinal discomfort.
- Frequency: Depending on the dosage, clinicians may prescribe 100 mg nightly or 200 mg divided into two doses (morning and night) to sustain plasma levels.
- Missed dose: If a dose is forgotten within 12 hours, take it as soon as remembered; otherwise skip and continue the regular schedule-do not double-dose.
- Travel: Pack tablets in original containers; the hormone is stable at room temperature, but avoid prolonged exposure to high heat or humidity.
- Interactions: Avoid concomitant use of strong CYP3A4 inducers (e.g., rifampicin) which may lower progesterone concentrations.
Understanding Side Effects and How to Manage Them
Common side effects such as mild nausea, breast tenderness, and dizziness arise from progesterone’s interaction with gastro-intestinal receptors and its influence on fluid balance. To minimise nausea, take the tablet with a meal and stay hydrated. Breast tenderness often resolves after the first treatment cycle; a supportive bra can provide comfort. Dizziness may be reduced by rising slowly from a seated position. Rare but serious reactions-such as severe allergic responses, unexplained vaginal bleeding, or signs of venous thromboembolism (leg swelling, chest pain, sudden shortness of breath)-necessitate immediate medical attention. Prompt reporting ensures timely intervention and adjustment of therapy.
Buying Prometrium from Our Online Pharmacy
Why Choose Our Service?
Accessing hormone therapy can be challenging due to limited pharmacy stock or insurance constraints. Our online pharmacy bridges that gap, delivering Prometrium discreetly and affordably to Singapore homes. By leveraging partnered licensed suppliers, we maintain stringent quality standards while offering competitive pricing that often undercuts brick-and-mortar outlets.
Quality & Safety
We work with internationally accredited partners who adhere to Good Manufacturing Practices (GMP) and WHO-recognized quality benchmarks, ensuring each tablet meets the potency and purity required for safe hormone replacement.
Pricing & Access
Our platform provides a clear price structure, with up to 30 % savings on the 200 mg pack compared with standard retail rates. Repeat orders qualify for a lifetime 10 % discount, making long-term therapy financially sustainable. Alternative progesterone products, such as micronised capsules, are also listed for comparison.
Discreet Delivery
Orders are packaged in unmarked, tamper-evident envelopes and dispatched via express (≈ 7 days) or standard (≈ 3 weeks) shipping options, preserving privacy throughout the fulfillment process.
Frequently Asked Questions
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How quickly will I feel the effects of Prometrium? Most women notice a reduction in menstrual irregularities or menopausal symptoms within two to three weeks, as steady progesterone levels are achieved.
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Can I switch from a compounded progesterone cream to Prometrium tablets? Transitioning is possible, but dosing must be adjusted under medical guidance to match serum concentrations and avoid hormonal spikes.
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Is it safe to use Prometrium while taking estrogen-based HRT? Yes, progesterone is essential in combined HRT for women with a uterus to counterbalance estrogen-induced endometrial proliferation.
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What should I do if I experience persistent mood changes? While some mood fluctuations are common, ongoing depression or anxiety warrants a clinician’s review to assess whether dosage adjustment or adjunct therapy is needed.
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Can men use Prometrium for any condition? Progesterone is occasionally prescribed off-label for male hypogonadism, but such use remains investigational and is not approved in Singapore.
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How does Prometrium compare with natural progesterone supplements? Micronised progesterone tablets provide more predictable absorption and plasma levels than many over-the-counter herbal preparations, which often contain variable bioactive constituents.
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Will taking Prometrium affect my cholesterol levels? Progesterone may modestly raise HDL cholesterol; routine lipid monitoring is advisable for patients with existing dyslipidaemia.
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Is it necessary to have regular blood tests while on Prometrium? Periodic assessment of hormone levels and liver function is recommended to ensure therapeutic efficacy and safety.
Glossary
- Micronised
- A process that reduces particle size to enhance dissolution and intestinal absorption of poorly soluble compounds.
- Luteal phase
- The post-ovulatory segment of the menstrual cycle during which progesterone prepares the uterine lining for possible implantation.
- Endometrial decidualisation
- The transformation of endometrial stromal cells under progesterone influence, creating a supportive environment for embryo implantation.
- CYP3A4
- A liver enzyme that metabolises many drugs; inducers can lower plasma concentrations of progesterone.
- Good Manufacturing Practices (GMP)
- Regulatory standards ensuring that pharmaceutical products are consistently produced and controlled to quality specifications.
Disclaimer
The information provided about Prometrium is for general knowledge only. It does not replace professional medical consultation. All treatment decisions, including those regarding off-label use, should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Prometrium for individuals who may have limited availability through traditional pharmacies, prescription-based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.
