Buy Tricor

Tricor

Generic Tricor (fenofibrate) is a lipid-modifying agent prescribed to adults in Singapore who need additional support for cardiovascular health. It belongs to the class of fibrates and works primarily by lowering elevated triglyceride levels while modestly raising high-density lipoprotein (HDL) cholesterol. In Singapore, fenofibrate is available by prescription only and is commonly used when lifestyle changes and statin therapy do not fully achieve target lipid profiles. Though its brand name is Tricor, the formulation contains the active ingredient fenofibrate, which is the same molecule found in other generic products worldwide. Understanding how this medication functions, when it is appropriate, and how to use it safely can help you make informed decisions about your heart-health regimen.

What is Generic Tricor (fenofibrate)?

Generic Tricor (fenofibrate) is a prescription-only oral medication classified as a fibrate, a subgroup of lipid-lowering agents. Approved by the Health Sciences Authority (HSA) of Singapore, it is indicated for the reduction of triglycerides, the management of mixed dyslipidaemia, and, in some patients, the modest increase of HDL-cholesterol. The product is supplied as a hard tablet (pill) in strengths of 160 mg and 200 mg. Because it contains fenofibrate, the drug exerts its effect through activation of peroxisome proliferator-activated receptor-α (PPAR-α), a nuclear receptor that regulates genes involved in lipid metabolism.

How Tricor Works

Fenofibrate binds to PPAR-α, forming a heterodimer with the retinoid X receptor. This complex attaches to specific DNA response elements, altering transcription of several key enzymes:

• Increased lipoprotein lipase activity - accelerates hydrolysis of triglyceride-rich very-low-density lipoproteins (VLDL) and chylomicrons, reducing circulating triglycerides.
• Reduced apolipoprotein C-III synthesis - diminishes inhibition of lipoprotein lipase, further enhancing triglyceride clearance.
• Enhanced hepatic β-oxidation - promotes breakdown of fatty acids, limiting hepatic VLDL production.
• Modest up-regulation of apolipoprotein A-I - contributes to a slight rise in HDL-cholesterol.

Pharmacokinetically, fenofibrate is absorbed best when taken with a fatty meal, reaching peak plasma concentrations within 2-4 hours. It is highly protein-bound, metabolised primarily by hydrolysis to fenofibric acid, and eliminated via the kidneys. The half-life ranges from 20 hours (160 mg) to 24 hours (200 mg), allowing once-daily dosing.

Why Tricor Is Used for Cardiovascular Care

• Hypertriglyceridaemia - Elevated triglycerides (> 2.3 mmol/L) increase the risk of pancreatitis and may contribute to atherogenic remnant particles. By markedly lowering triglycerides, Tricor reduces this risk.
• Mixed Dyslipidaemia - Patients on statins sometimes retain high triglycerides or low HDL despite optimal LDL control. Tricor’s dual action on triglycerides and HDL makes it a valuable adjunct.
• Secondary Prevention in Diabetic Patients - Guidelines endorse fibrates for diabetic individuals with triglycerides > 2.3 mmol/L, as they experience a higher cardiovascular event rate.
• Guideline Position - The 2022 ESC/EAS lipid guidelines list fibrates as a class IIb recommendation for patients with severe hypertriglyceridaemia (> 5.6 mmol/L) or when statins alone are insufficient.

Compared with omega-3 fatty acids, Tricor generally achieves a greater reduction in triglycerides within weeks, though omega-3s may be preferred when patients have very high triglycerides (> 10 mmol/L) due to a more favorable safety profile in certain populations.

Off-Label and Investigational Uses of Tricor

Evidence from small-scale trials suggests fenofibrate may have modest benefits in slowing the progression of diabetic retinopathy and in reducing markers of inflammation in chronic kidney disease. However, these uses are not approved by the HSA in Singapore, and larger studies have yielded mixed results. Off-label use should only be considered under the supervision of a qualified healthcare provider.

Is Tricor Right for You?

Tricor is most appropriate for adults who:

• Have fasting triglyceride levels ≥ 2.3 mmol/L despite lifestyle optimisation and statin therapy.
• Are at moderate to high cardiovascular risk, especially if diabetic or metabolic syndrome is present.
• Do not have severe hepatic impairment (Child-Pugh C) or known hypersensitivity to fenofibrate.

Pregnancy and lactation are contraindications, as the drug crosses the placenta and is excreted in breast milk. Elderly patients generally tolerate Tricor well, but dose adjustments may be needed for those with reduced renal function (creatinine clearance < 30 mL/min).

Taking Tricor Effectively

1. Timing: Take the tablet with the main meal of the day (breakfast or dinner) to maximise absorption.
2. Food Interaction: A high-fat meal improves bioavailability; a low-fat snack may lead to sub-therapeutic levels.
3. Missed Dose: If you forget a dose, take it as soon as you remember provided it is still before the next scheduled dose. Do not double-dose.
4. Travel Tips: Carry the medication in its original container, keep it in a cool, dry place, and ensure you have enough supply for the trip’s duration.
5. Lifestyle Integration: Combine Tricor with a heart-healthy diet (rich in omega-3 fatty acids, low in refined carbohydrates) and regular aerobic exercise for synergistic lipid-lowering effects.

Understanding Side Effects and How to Manage Them

Most patients experience mild, transient side effects related to fenofibrate’s influence on hepatic metabolism:

• Gastrointestinal upset (nausea, abdominal discomfort) - usually resolves within a week; taking the tablet with a larger meal can alleviate symptoms.
• Elevated liver enzymes - monitor transaminases at baseline and after 6-12 weeks; if levels rise > 3 × ULN, consider dose reduction or discontinuation.
• Myopathy - rare but more likely when combined with statins; any unexplained muscle pain or weakness warrants prompt medical review.

Serious adverse events such as gallstones or severe hepatotoxicity are uncommon. Seek immediate medical attention for jaundice, dark urine, or persistent muscle pain with weakness.

Buying Tricor from Our Online Pharmacy

Choosing our online pharmacy gives you a discreet, reliable pathway to obtain Tricor when local pharmacies face stock shortages or when you prefer the convenience of home delivery.

Why Choose Our Service?

Our platform partners with licensed international distributors that comply with Singapore’s regulatory standards, ensuring each batch of Tricor meets stringent quality controls.

Quality & Safety

We work with suppliers that adhere to Good Manufacturing Practice (GMP) and WHO-certified standards, providing you with authentic medication that matches the exact composition of the brand product.

Pricing & Access

Generic Tricor tablets are priced competitively, often 30-40 % lower than the branded version. As a new customer, you receive a Lifetime 10 % discount on all reorders, making long-term therapy more affordable.

Discreet Delivery

Orders are shipped in unmarked packaging; express delivery arrives in approximately 7 days, while standard service takes up to 3 weeks. All shipments comply with Singapore customs regulations.

Frequently Asked Questions

• What blood tests are needed before starting Tricor? Baseline fasting lipid panel, liver function tests, and renal function assessment are recommended to ensure safe initiation and to establish a reference point for monitoring.

• Can I take Tricor together with a statin? Combination therapy is common for mixed dyslipidaemia. Your doctor will evaluate the risk of myopathy and may adjust the statin dose accordingly.

• How quickly will my triglyceride levels improve? Most patients see a 30-50 % reduction within 4-6 weeks of consistent daily dosing, provided they adhere to dietary recommendations.

• Is Tricor safe for people with mild kidney disease? Yes, but dose adjustment may be required for creatinine clearance below 30 mL/min. Your physician will determine the appropriate regimen.

• Will Tricor affect my blood sugar control? Fenofibrate has a neutral effect on glucose metabolism; however, regular monitoring is advised for diabetic patients.

• Can I switch from another fibrate to Tricor? A direct switch is possible, but it should be supervised by a clinician to avoid overlapping therapy and to monitor for adverse reactions.

• What should I do if I experience muscle pain? Stop the medication and contact your healthcare provider immediately; they may check creatine kinase levels and decide whether to discontinue therapy.

• Is there a difference between the 160 mg and 200 mg tablets? The 200 mg strength provides a higher dose for patients requiring a more aggressive triglyceride reduction, while the 160 mg is often sufficient for moderate elevations.

Glossary

Fibrate

A class of drugs that activate PPAR-α to modify lipid metabolism, primarily lowering triglycerides and modestly raising HDL-cholesterol.

PPAR-α (Peroxisome Proliferator-Activated Receptor-α)

A nuclear receptor that regulates genes involved in fatty acid oxidation and lipoprotein metabolism.

Triglycerides

A type of fat in the blood; high levels are linked to pancreatitis and increased cardiovascular risk.

HDL-cholesterol

High-density lipoprotein; often called “good” cholesterol because it helps remove excess cholesterol from arterial walls.

CYP450 enzymes

Liver enzymes responsible for drug metabolism; fenofibrate is minimally metabolised by this pathway, reducing drug-drug interaction risk.

Disclaimer

The information provided about Tricor is for general knowledge only and does not replace professional medical consultation. All treatment decisions, including those regarding off-label use, should be made under the supervision of a qualified healthcare provider. We assume all readers are responsible adults capable of making informed decisions about their health. Our online pharmacy offers access to Tricor for individuals who may have limited availability through traditional pharmacies, prescription-based insurance schemes, or who are seeking affordable generic alternatives. Always consult your doctor before starting, changing, or discontinuing any medication.

External Resources about Tricor

• Tricor: Uses, Dosage & Side Effects - Drugs.com
• TriCor: Uses, Dosage, Side Effects, Food Interaction & FAQ
• Tricor, Lofibra tablets (fenofibrate) dosing, indications, interactions, adverse effects, and more
• TRICOR (fenofibrate) Tablet, for oral use - Food and Drug …
• Tricor (A-S Medication Solutions): FDA Package Insert